These two chemokines mediate neutrophil, lymphocyte and monocyte/macrophage infiltration into tissues. IL-17A (0C10 ng/ml) but not at higher concentrations. Conclusions IL-17A-induced production of inflammatory mediators by ARPE-19 cells entails Erk1/2, p38MAPK, PI3K-Akt and NF-B pathways. Intro Uveitis is definitely a common intraocular inflammatory disease. Recent studies have shown that helper T lymphocyte (Th)17 cells are … Continue reading These two chemokines mediate neutrophil, lymphocyte and monocyte/macrophage infiltration into tissues